Journal article
A prospective controlled study of sexual function and sexually related personal distress up to 12 months after premenopausal risk-reducing bilateral salpingo-oophorectomy
RM Islam, SR Davis, RJ Bell, T Tejada-Berges, CD Wrede, SM Domchek, B Meiser, J Kirk, EO Krejany, M Hickey
Menopause | Published : 2021
Abstract
Objective:Premenopausal risk-reducing bilateral salpingo-oophorectomy (RRBSO) may impair sexual function, but the nature and degree of impairment and impact of estrogen therapy on sexual function and sexually related personal distress after RRBSO are uncertain.Methods:Prospective observational study of 73 premenopausal women at elevated risk of ovarian cancer planning RRBSO and 68 premenopausal controls at population risk of ovarian cancer. Participants completed the Female Sexual Function Index and the Female Sexual Distress Scale-Revised. Change from baseline in sexual function following RRBSO was compared with controls at 12 months according to estrogen therapy use.Results:Baseline sexual..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
In Australia this study was financially supported by the NationalHealth and Medical Research Council (NHMRC; Canberra, Australia; Grant #APP1048023), and by philanthropic funding provided by The Royal Women's Hospital (Melbourne, Australia), The Women's Foundation (Melbourne, Australia), the Australia and New Zealand Gynecological Oncology Group (ANZGOG; Sydney, Australia), and the Westmead Hospital Familial Cancer Service (Sydney, Australia). In the USA this study was financially supported by philanthropic funding provided by the Basser Center for BRCA (Philadelphia, PA) and Susan G. Komen (Dallas, TX; Grant #SAC150003). M.H. is supported by a NHMRC Practitioner Fellowship (Grant #1058935). S.R.D. is supported by a NHMRC Senior Principal Research Fellowship (Grant #1135843). B.M. is supported by a NHMRC Senior Research FellowshipLevel B (Grant #1078523). S.M.D. is supported by Susan G. Komen organization. This study was also supported by Register4 through its members' participation in research and/or provision of samples and information (register4.org.au).